Modulation of Biofilm Exopolysaccharides by the Streptococcus mutans vicX Gene
نویسندگان
چکیده
منابع مشابه
Modulation of Biofilm Exopolysaccharides by the Streptococcus mutans vicX Gene
The cariogenic pathogen Streptococcus mutans effectively utilizes dietary sucrose for the synthesis of exopolysaccharide, which act as a scaffold for its biofilm, thus contributing to its pathogenicity, environmental stress tolerance, and antimicrobial resistance. The two-component system VicRK of S. mutans regulates a group of virulence genes that are associated with biofilm matrix synthesis. ...
متن کاملThe Streptococcus mutans vicX gene product modulates gtfB/C expression, biofilm formation, genetic competence, and oxidative stress tolerance.
Streptococcus mutans is considered one of the primary etiologic agents of dental caries. Previously, we characterized the VicRK two-component signal transduction system, which regulates multiple virulence factors of S. mutans. In this study, we focused on the vicX gene of the vicRKX tricistronic operon. To characterize vicX, we constructed a nonpolar deletion mutation in the vicX coding region ...
متن کاملThe Streptococcus mutans vicX gene product modulates gtfB / C Expression , Biofilm Formation , 4 Genetic Competence and Oxidative Stress Tolerance
*Corresponding author. 22 Mailing address: 23 Rm. 449A Dental Research Institute 24 124 Edward Street 25 Toronto, ON M51G6 26 Canada 27 Phone: (416) 979-4917 ext. 4592 28 Fax: (416) 979-4936 29 E-mail: [email protected] 30 AC CE P ED Copyright © 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.01161-06...
متن کامل[Assessment of gene associated with Streptococcus mutans biofilm formation].
Streptococcus mutans, the primary etiological agent of human dental caries and an obligate biofilm-forming bacterium, has developed a variety of mechanisms to colonize the tooth surface. Oral transmission of S. mutans through contact between mother and child is thought to be one of the risks of developing dental caries. In this study, I surveyed oral transmission frequency of S. mutans from mot...
متن کاملBiofilm Formation by Streptococcus mutans and Related Bacteria
Caries is a disease of human dentition characterized by the loss of mineralized surfaces of the toot di non-specific removal of plaque by mechanical means such as brushing, although it is difficu this method. Caries is also a widespread infection in children. Streptococcus mutans and S. gents of caries heres to the en ria.
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2015
ISSN: 1664-302X
DOI: 10.3389/fmicb.2015.01432